Backed by over 30 years of clinical science
Not all skincare is created equal. If you’re ready to stop guessing and start glowing, ZO is your next step.
Best sellers
ZO® Daily Power Defense
This award-winning antioxidant serum is a cornerstone of any ZO regimen. Daily Power Defense strengthens skin’s barrier, repairs DNA damage, and defends against premature aging. Think of it as your daily insurance policy for healthy, resilient, youthful skin.
Ideal For:
Fine lines & wrinkles
Environmental damage
All skin types, especially aging or compromised
Why You'll Love It:
Stimulates collagen and elastin
Neutralizes free radicals and pollutants
Strengthens skin from within
How to Use:
Apply 1–2 pumps to clean, dry skin every morning (after serums, before SPF).
Pro Tip: Pair with a ZO retinol in the evening for next-level results.
Your skin deserves more than over-the-counter.
Explore ZO’s most powerful solutions
Anti-Aging
Anti-Aging
Best Sellers
Best Sellers
Programs & Kits
Programs & Kits
Sunscreen
Sunscreen
Sensitive Skin
Sensitive Skin